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About the nelm | help & support | site feedback | update newsletter subscription homepage login | register search the nelm medicines a-z find key information about medicines by name (prototype) browse by categories: bnf category | medical specialty | national health service | medicines information browse by nelm area: evidence | other library updates | news | health in focus | medicines a-z | communities | useful links | formularies nelm news service rct: cisplatin/s-1 vs cisplatin/ fluorouracil for advanced gastric or gastroesophageal cancer source: jco date published: 17/02/2010 15:30 summary by: sheetal ladva cisplatin and fluoropyrimidine are the most frequently prescribed agents to treat advanced gastric adenocarcinoma and this combination has been used as a reference for comparison with newer treatments. Price of 20mg viagra However, this combination is associated with considerable adverse effects and inconveniences. More recently, s-1, a fourth generation oral fluoropyrimidine containing tegafur/gimeracil/oteracil potassium,  has been approved in the far east for the treatment of advanced gastric cancer and is said to be more advantageous. viagra online The authors of this phase iii study compared the safety and efficacy of cisplatin/s-1 to cisplatin/infusional fluorouracil in a global non-asian population.   the researchers randomised 1, 053 patients with advanced, untreated gastric, or gastroesophageal adenocarcinoma from 24 countries to s-1 (50 mg/m2 for 21 days) and cisplatin (75 mg/m2 on day 1, repeated every 28 days) or infusional fluorouracil (1,000 mg/m2/24 hours for great hundred hours) and cisplatin (100 mg/m2 on day 1, repeated every 28 days). viagra lilly original   there was no statistically significant difference in the primary end point, overall survival (os) (8. cheap viagra 6 months vs 7. cheap viagra online 9 months ; hr, 0. can buy viagra safely online 92; 95% ci, 0. buy cheap viagra 80 to 1. 05; p = 0. 20). viagra 20 mg split in half   the cisplatin/s-1 arm was associated with a significantly improved safety profile compared with the cisplatin/infusional fluorouracil arm for the rates of grade 3/4 neutropaenia (32. 3% v 63. 6%), complicated neutropenia (5. ice cream made viagra 0% v 14. viagra 20 mg split in half 4%), stomatitis (1. 3% v 13. viagra for sale 6%), hypokalaemia (3. cheap viagra 6% v 10. 8%), and treatment-related deaths (2. Viagra coupons manufacturer 5% v 4. viagra 20 mg split in half 9%; p < 0. 05). buy viagra online   the authors concluded that cisplatin/s-1 did not have a statistically significant impact on os in patients with advanced gastric or gastroesophageal adenocarcinoma compared with cisplatin/infusional fluorouracil, but it did result in a significantly improved safety profile. About this library entry category: 8. generic viagra online 1. 3 antimetabolites | 8. http://floridalighttacklecharters.com/thq-buy-viagra-canada-uk/ 1. 5 other antineoplastic drugs | cancer: gastroenterological nelm area:  news abstract preview your comment add new comment comment text: comments there are no comments yet. You could be the first! You must be logged in to comment. Generic viagra no rx Printer friendly version related evidence 8. cheap viagra online 1. role of viagra in women 3 antimetabolites 11/09/2012 smc accepts restricted use of tegafur/gimeracil/oteracil (teysunoâ„¢) for advanced gastric cancer 14/08/2012 smc accepts mercaptopurine suspension (xalupr. To change this page, upload your website into the public_html directory
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